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Digital-Direct-RT-PCR: a sensitive and specific method for quantification of CTC in patients with cervical carcinoma

The detection of circulating tumour cells (CTC) in cancer patients may be useful for therapy monitoring and prediction of relapse. A sensitive assay based on HPV-oncogene transcripts which are highly specific for cervical cancer cells was established. The Digital-Direct-RT-PCR (DD-RT-PCR) combines F...

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Dettagli Bibliografici
Autori principali: Pfitzner, Claudia, Schröder, Isabel, Scheungraber, Cornelia, Dogan, Askin, Runnebaum, Ingo Bernhard, Dürst, Matthias, Häfner, Norman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913920/
https://ncbi.nlm.nih.gov/pubmed/24496006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03970
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