Abnormal Intracellular Calcium Signaling and SNARE-Dependent Exocytosis Contributes to SOD1G93A Astrocyte-Mediated Toxicity in Amyotrophic Lateral Sclerosis

Motor neurons are progressively and predominantly degenerated in ALS, which is not only induced by multiple intrinsic pathways but also significantly influenced by the neighboring glial cells. In particular, astrocytes derived from the SOD1 mutant mouse model of ALS or from human familial or sporadi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kawamata, Hibiki, Ng, Seng Kah, Diaz, Natalia, Burstein, Suzanne, Morel, Lydie, Osgood, Alexandra, Sider, Brittany, Higashimori, Haruki, Haydon, Philip G., Manfredi, Giovanni, Yang, Yongjie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2014
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913875/
https://ncbi.nlm.nih.gov/pubmed/24501372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2689-13.2014
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