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Precise Control of Movement Kinematics by Optogenetic Inhibition of Purkinje Cell Activity

Purkinje cells (PCs) of the cerebellar cortex are necessary for controlling movement with precision, but a mechanistic explanation of how the activity of these inhibitory neurons regulates motor output is still lacking. We used an optogenetic approach in awake mice to show for the first time that tr...

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Detalhes bibliográficos
Main Authors: Heiney, Shane A., Kim, Jinsook, Augustine, George J., Medina, Javier F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913874/
https://ncbi.nlm.nih.gov/pubmed/24501371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4547-13.2014
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