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Precise Control of Movement Kinematics by Optogenetic Inhibition of Purkinje Cell Activity

Purkinje cells (PCs) of the cerebellar cortex are necessary for controlling movement with precision, but a mechanistic explanation of how the activity of these inhibitory neurons regulates motor output is still lacking. We used an optogenetic approach in awake mice to show for the first time that tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Heiney, Shane A., Kim, Jinsook, Augustine, George J., Medina, Javier F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913874/
https://ncbi.nlm.nih.gov/pubmed/24501371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4547-13.2014
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