Induction of Specific Humoral and Cellular Immune Responses in a Mouse Model following Gene Fusion of HSP70C and Hantaan Virus Gn and S0.7 in an Adenoviral Vector

Heat shock proteins (HSPs) display adjuvant functions when given as fusion proteins to enhance vaccination efficiency. To evaluate enhanced potency of Hantaan virus (HTNV) glycoprotein (GP) and nucleocapsid protein (NP) immunogenicity by heat shock protein 70 (HSP70), a recombinant adenovirus rAd-Gn...

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Bibliographic Details
Main Authors: Cheng, Linfeng, Yu, Lan, Wu, Xingan, Li, Kai, Wang, Fang, Zhang, Liang, Ye, Wei, Li, Puyuan, Zhang, Fanglin, Xu, Zhikai
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913774/
https://ncbi.nlm.nih.gov/pubmed/24505421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088183
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