A recombinant pseudotyped lentivirus expressing the envelope glycoprotein of Hantaan virus induced protective immunity in mice

BACKGROUND: Hantaviruses cause acute hemorrhagic fever with renal syndrome (HFRS). Currently, several types of inactivated HFRS vaccines are widely used, however the limited ability of these immunogen to elicit neutralizing antibodies restricts vaccine efficacy. Development of an effective vaccine t...

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Main Authors: Yu, Lan, Bai, Wentao, Wu, Xingan, Zhang, Liang, Zhang, Lei, Li, Puyuan, Wang, Fang, Liu, Ziyu, Zhang, Fanglin, Xu, Zhikai
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851560/
https://ncbi.nlm.nih.gov/pubmed/24093752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-301
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