Mycobacterium tuberculosis Cyclophilin A Uses Novel Signal Sequence for Secretion and Mimics Eukaryotic Cyclophilins for Interaction with Host Protein Repertoire

Cyclophilins are prolyl isomerases with multitude of functions in different cellular processes and pathological conditions. Cyclophilin A (PpiA) of Mycobacterium tuberculosis is secreted during infection in intraphagosomal niche. However, our understanding about the evolutionary origin, secretory me...

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Detalhes bibliográficos
Main Authors: Bhaduri, Asani, Misra, Richa, Maji, Abhijit, Bhetaria, Preetida J., Mishra, Sonakshi, Arora, Gunjan, Singh, Lalit Kumar, Dhasmana, Neha, Dubey, Neha, Virdi, Jugsharan Singh, Singh, Yogendra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913756/
https://ncbi.nlm.nih.gov/pubmed/24505389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088090
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