Mycobacterium tuberculosis Cyclophilin A Uses Novel Signal Sequence for Secretion and Mimics Eukaryotic Cyclophilins for Interaction with Host Protein Repertoire

Cyclophilins are prolyl isomerases with multitude of functions in different cellular processes and pathological conditions. Cyclophilin A (PpiA) of Mycobacterium tuberculosis is secreted during infection in intraphagosomal niche. However, our understanding about the evolutionary origin, secretory me...

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Hlavní autoři: Bhaduri, Asani, Misra, Richa, Maji, Abhijit, Bhetaria, Preetida J., Mishra, Sonakshi, Arora, Gunjan, Singh, Lalit Kumar, Dhasmana, Neha, Dubey, Neha, Virdi, Jugsharan Singh, Singh, Yogendra
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913756/
https://ncbi.nlm.nih.gov/pubmed/24505389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088090
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