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Loss of Igfbp7 Causes Precocious Involution in Lactating Mouse Mammary Gland

BACKGROUND: Insulin like growth factors (IGFs) and their binding proteins (IGFBPs) are secreted peptides that play major roles in regulating the normal development and maturation of mammary gland. While Igfbp7 has been shown to decrease breast tumor growth, its role in regulating the normal mammary...

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Autori principali: Chatterjee, Sumanta, Bacopulos, Stephanie, Yang, Wenyi, Amemiya, Yutaka, Spyropoulos, Demetri, Raouf, Afshin, Seth, Arun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913705/
https://ncbi.nlm.nih.gov/pubmed/24505323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087858
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