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Loss of Igfbp7 Causes Precocious Involution in Lactating Mouse Mammary Gland

BACKGROUND: Insulin like growth factors (IGFs) and their binding proteins (IGFBPs) are secreted peptides that play major roles in regulating the normal development and maturation of mammary gland. While Igfbp7 has been shown to decrease breast tumor growth, its role in regulating the normal mammary...

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Autors principals: Chatterjee, Sumanta, Bacopulos, Stephanie, Yang, Wenyi, Amemiya, Yutaka, Spyropoulos, Demetri, Raouf, Afshin, Seth, Arun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913705/
https://ncbi.nlm.nih.gov/pubmed/24505323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087858
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