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Choose Your Label Wisely: Water-Soluble Fluorophores Often Interact with Lipid Bilayers

Water-soluble organic fluorophores are widely used as labels in biological systems. However, in many cases these fluorophores can interact strongly with lipid bilayers, influencing the interaction of the target with the bilayer and/or leading to misleading fluorescent signals. Here, we quantify the...

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Détails bibliographiques
Auteurs principaux: Hughes, Laura D., Rawle, Robert J., Boxer, Steven G.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913624/
https://ncbi.nlm.nih.gov/pubmed/24503716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087649
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