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Choose Your Label Wisely: Water-Soluble Fluorophores Often Interact with Lipid Bilayers

Water-soluble organic fluorophores are widely used as labels in biological systems. However, in many cases these fluorophores can interact strongly with lipid bilayers, influencing the interaction of the target with the bilayer and/or leading to misleading fluorescent signals. Here, we quantify the...

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Bibliografiske detaljer
Main Authors: Hughes, Laura D., Rawle, Robert J., Boxer, Steven G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913624/
https://ncbi.nlm.nih.gov/pubmed/24503716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087649
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