Specific sequences commonly found in the V3 domain of HIV-1 subtype C isolates affect the overall conformation of native Env and induce a neutralization-resistant phenotype independent of V1/V2 masking

Primary HIV-1 isolates are relatively resistant to neutralization by antibodies commonly induced after infection or vaccination. This is generally attributed to masking of sensitive epitopes by the V1/V2 domain and/or glycans situated at various positions in Env. Here we identified a novel masking e...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Salomon, Aidy, Krachmarov, Chavdar, Lai, Zhong, Honnen, William, Zingman, Barry S., Sarlo, Julie, Gorny, Miroslaw K., Zolla-Pazner, Susan, Robinson, James E., Pinter, Abraham
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913561/
https://ncbi.nlm.nih.gov/pubmed/24314667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.10.007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados