Nasal absorption of insulin: enhancement by hydrophobic bile salts.
We demonstrate that therapeutically useful amounts of insulin are absorbed by the nasal mucosa of human beings when administered as a nasal spray with the common bile salts. By employing a series of bile salts with subtle differences in the number, position, and orientation of their nuclear hydroxyl...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1985
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391356/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3903753/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.21.7419 |
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