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Nasal absorption of insulin: enhancement by hydrophobic bile salts.

We demonstrate that therapeutically useful amounts of insulin are absorbed by the nasal mucosa of human beings when administered as a nasal spray with the common bile salts. By employing a series of bile salts with subtle differences in the number, position, and orientation of their nuclear hydroxyl...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Gordon, G S, Moses, A C, Silver, R D, Flier, J S, Carey, M C
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1985
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391356/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3903753/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.21.7419
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