Designing Lead Optimisation of MMP-12 Inhibitors

The design of new molecules with desired properties is in general a very difficult problem, involving heavy experimentation with high investment of resources and possible negative impact on the environment. The standard approach consists of iteration among formulation, synthesis, and testing cycles,...

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Bibliographic Details
Main Authors: Borrotti, Matteo, De March, Davide, Slanzi, Debora, Poli, Irene
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913506/
https://ncbi.nlm.nih.gov/pubmed/24527058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/258627
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