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Positive feedback between PU.1 and the cell cycle controls myeloid differentiation()

Regulatory gene circuits with positive feedback loops control stem cell differentiation, but several mechanisms can contribute to positive feedback. Here, we dissect feedback mechanisms through which the transcription factor PU.1 controls lymphoid and myeloid differentiation. Quantitative live-cell...

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Autori principali: Kueh, Hao Yuan, Champhekhar, Ameya, Nutt, Stephen L., Elowitz, Michael B., Rothenberg, Ellen V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913367/
https://ncbi.nlm.nih.gov/pubmed/23868921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1240831
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