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Cyclosporine and Herbal Supplement Interactions

Cyclosporine (CyA) is a well-known immunosuppressant with a narrow therapeutic window. Its bioavailability is affected by many other traditional drugs and herbal extracts. Cytochrome P-450 isoenzymes CYP3A4 and CYP3A5 and protein P-glycoprotein (P-gp) are involved in CyA bioavailability. Interaction...

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Detalhes bibliográficos
Main Authors: Colombo, D., Lunardon, L., Bellia, G.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913293/
https://ncbi.nlm.nih.gov/pubmed/24527031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/145325
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