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Evaluation of cyclosporin-phenytoin interaction with observations on cyclosporin metabolites.

We have observed that patients on concurrent cyclosporin and phenytoin therapy required increased doses of cyclosporin to maintain therapeutic concentrations of this novel immunosuppressive drug. We have, therefore, studied the influence of phenytoin on the pharmacokinetics of oral cyclosporin in si...

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Detalhes bibliográficos
Main Authors: Freeman, D J, Laupacis, A, Keown, P A, Stiller, C R, Carruthers, S G
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463670/
https://ncbi.nlm.nih.gov/pubmed/6529529
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