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Site-specific carcinogen binding to DNA in polytene chromosomes.

Treatment of Chironomus polytene chromosomes with the ultimate carcinogen benzo[a]pyrene diol epoxide I or in vivo administration of the parent hydrocarbon to larvae indicates that the carcinogen interacts with the genome in a nonrandom manner. Visualization of the carcinogen-DNA binding sites by im...

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Bibliografiske detaljer
Main Authors: Kurth, P D, Bustin, M
Format: Artigo
Sprog:Inglês
Udgivet: 1985
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC391313/
https://ncbi.nlm.nih.gov/pubmed/3931083
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