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Site-specific carcinogen binding to DNA.

Benzo[alpha]pyrene diol epoxide (BPDE) is a well-studied environmental carcinogen that binds covalently to DNA. Here we describe a photochemical technique that allows us to map BPDE-binding sites within cloned gene sequences. The technique is based upon our observation that, when irradiated with las...

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Bibliografiske detaljer
Main Authors: Boles, T C, Hogan, M E
Format: Artigo
Sprog:Inglês
Udgivet: 1984
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC391762/
https://ncbi.nlm.nih.gov/pubmed/6435118
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