Impact of promoter polymorphisms in key regulators of the intrinsic apoptosis pathway on the outcome of childhood acute lymphoblastic leukemia

The introduction of multiagent treatment protocols has led to a remarkable increase in survival rates for children diagnosed with acute lymphoblastic leukemia, yet for a subpopulation of patients, resistance to chemotherapeutics remains an obstacle to successful treatment. Here we investigate the ro...

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Hlavní autoři: Sanchez, Rocio, St-Cyr, Janick, Lalonde, Marie-Eve, Healy, Jasmine, Richer, Chantal, Gagné, Vincent, Laverdière, Caroline, Silverman, Lewis B., Sallan, Stephen E., Neuberg, Donna, Kutok, Jeffery L., Kritikou, Ekaterini A., Krajinovic, Maja, Sinnett, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912962/
https://ncbi.nlm.nih.gov/pubmed/24038028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.085340
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