The identification of mitochondrial DNA variants in glioblastoma multiforme

BACKGROUND: Mitochondrial DNA (mtDNA) encodes key proteins of the electron transfer chain (ETC), which produces ATP through oxidative phosphorylation (OXPHOS) and is essential for cells to perform specialised functions. Tumor-initiating cells use aerobic glycolysis, a combination of glycolysis and l...

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Bibliographic Details
Main Authors: Yeung, Ka Yu, Dickinson, Adam, Donoghue, Jacqueline F, Polekhina, Galina, White, Stefan J, Grammatopoulos, Dimitris K, McKenzie, Matthew, Johns, Terrance G, John, Justin C St
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912901/
https://ncbi.nlm.nih.gov/pubmed/24383468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-1
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