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The Emerging Role of Insulin and Insulin-Like Growth Factor Signaling in Cancer Stem Cells
Cancer cells frequently exploit the IGF signaling, a fundamental pathway mediating development, cell growth, and survival. As a consequence, several components of the IGF signaling are deregulated in cancer and sustain cancer progression. However, specific targeting of IGF-IR in humans has resulted...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3912738/ https://ncbi.nlm.nih.gov/pubmed/24550888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00010 |
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