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The Emerging Role of Insulin and Insulin-Like Growth Factor Signaling in Cancer Stem Cells

Cancer cells frequently exploit the IGF signaling, a fundamental pathway mediating development, cell growth, and survival. As a consequence, several components of the IGF signaling are deregulated in cancer and sustain cancer progression. However, specific targeting of IGF-IR in humans has resulted...

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Bibliographic Details
Main Authors: Malaguarnera, Roberta, Belfiore, Antonino
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912738/
https://ncbi.nlm.nih.gov/pubmed/24550888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00010
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