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Reduction of endoplasmic reticulum stress attenuates the defects caused by Drosophila mitofusin depletion

Ablation of the mitochondrial fusion and endoplasmic reticulum (ER)–tethering protein Mfn2 causes ER stress, but whether this is just an epiphenomenon of mitochondrial dysfunction or a contributor to the phenotypes in mitofusin (Mfn)-depleted Drosophila melanogaster is unclear. In this paper, we sho...

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Autors principals: Debattisti, Valentina, Pendin, Diana, Ziviani, Elena, Daga, Andrea, Scorrano, Luca
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912536/
https://ncbi.nlm.nih.gov/pubmed/24469638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201306121
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