Activation of PI3K signaling in Merkel cell carcinoma

PURPOSE: Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine tumor, often metastatic at presentation, for which current chemotherapeutic regimens are largely ineffective. As its pathogenesis is still unknown, we hypothesized that deregulation of signaling pathways commonly activate...

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Detalhes bibliográficos
Main Authors: Nardi, Valentina, Song, Young Chul, Santamaria-Barria, Juan A., Cosper, Arjola K., Lam, Quynh, Faber, Anthony C., Boland, Genevieve M., Yeap, Beow Y., Bergethon, Kristin, Scialabba, Vanessa L., Tsao, Hensin, Settleman, Jeffrey, Ryan, David P., Borger, Darrell R., Bhan, Atul, Hoang, Mai P., Iafrate, Anthony J., Cusack, James C., Engelman, Jeffrey A., Dias-Santagata, Dora
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912509/
https://ncbi.nlm.nih.gov/pubmed/22261808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2308
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