Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

Hybrid polar compounds, of which hexamethylenebisacetamide (HMBA) is the prototype, are potent inducers of differentiation of murine erythroleukemia (MEL) cells and a wide variety of other transformed cells. HMBA has been shown to induce differentiation of neoplastic cells in patients, but is not an...

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Autori principali: Richon, V M, Webb, Y, Merger, R, Sheppard, T, Jursic, B, Ngo, L, Civoli, F, Breslow, R, Rifkind, R A, Marks, P A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC39124/
https://ncbi.nlm.nih.gov/pubmed/8650156
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