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Importance of the pluripotency factor LIN28 in the mammalian nucleolus during early embryonic development

The maternal nucleolus is required for proper activation of the embryonic genome (EGA) and early embryonic development. Nucleologenesis is characterized by the transformation of a nucleolar precursor body (NPB) to a mature nucleolus during preimplantation development. However, the function of NPBs a...

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Detalhes bibliográficos
Main Authors: Vogt, Edgar J., Meglicki, Maciej, Hartung, Kristina Ilka, Borsuk, Ewa, Behr, Rüdiger
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912245/
https://ncbi.nlm.nih.gov/pubmed/23172912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.083279
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