Azacytidine-induced tumorigenesis of CHEF/18 cells: correlated DNA methylation and chromosome changes.

5-Azacytidine (azaC), a drug that induces decreased methylation of DNA in mammalian cells, was shown previously to induce differentiation of mesenchymal cell types in CHEF/18 cells (Chinese hamster embryo fibroblasts). This paper describes the effectiveness of azaC in inducing tumorigenicity in CHEF...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Harrison, J J, Anisowicz, A, Gadi, I K, Raffeld, M, Sager, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1983
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391218/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6195661/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.21.6606
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