Azacytidine-induced tumorigenesis of CHEF/18 cells: correlated DNA methylation and chromosome changes.
5-Azacytidine (azaC), a drug that induces decreased methylation of DNA in mammalian cells, was shown previously to induce differentiation of mesenchymal cell types in CHEF/18 cells (Chinese hamster embryo fibroblasts). This paper describes the effectiveness of azaC in inducing tumorigenicity in CHEF...
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| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
1983
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391218/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6195661/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.21.6606 |
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