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Circadian Rhythms of PER2::LUC in Individual Primary Mouse Hepatocytes and Cultures

BACKGROUND: Hepatocytes, the parenchymal cells of the liver, express core clock genes, such as Period2 and Cryptochrome2, which are involved in the transcriptional/translational feedback loop of the circadian clock. Whether or not the liver is capable of sustaining rhythms independent of a central p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guenthner, Casey J., Luitje, Martha E., Pyle, Lorna A., Molyneux, Penny C., Yu, Jimmy K., Li, Alexander S., Leise, Tanya L., Harrington, Mary E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911982/
https://ncbi.nlm.nih.gov/pubmed/24498336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087573
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