The CREB leucine zipper regulates CREB phosphorylation, cardiomyopathy, and lethality in a transgenic model of heart failure

Signaling through cAMP plays an important role in heart failure. Phosphorylation of cAMP response element binding protein (CREB) at serine-133 regulates gene expression in the heart. We examined the functional significance of CREB-S133 phosphorylation by comparing transgenic models in which a phosph...

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Detaylı Bibliyografya
Asıl Yazarlar: Huggins, Gordon S., Lepore, John J., Greytak, Sarah, Patten, Richard, McNamee, Rachel, Aronovitz, Mark, Wang, Paul J., Reed, Guy L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911886/
https://ncbi.nlm.nih.gov/pubmed/17616745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00516.2007
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