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Sustained inhibition of neovascularization in vldlr(−/−) mice following intravitreal injection of cerium oxide nanoparticles and the role of the ASK1-P38/JNK-NF-κB pathway

Cerium oxide nanoparticles (nanoceria) are direct antioxidants; they inhibit pathological neovascularization following a single intravitreal injection into new born very low density lipoprotein receptor knockout (vldlr(−/−)) mice. However, the long-term therapeutic effects and mechanisms of nanoceri...

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Hlavní autoři: Cai, Xue, Seal, Sudipta, McGinnis, James F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911773/
https://ncbi.nlm.nih.gov/pubmed/24140045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.10.022
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