Resistance to Infection, Early and Persistent Suppression of Simian Immunodeficiency Virus SIV(mac251) Viremia, and Significant Reduction of Tissue Viral Burden after Mucosal Vaccination in Female Rhesus Macaques

The efficacy of oral, intestinal, nasal, and vaginal vaccinations with DNA simian immunodeficiency virus (SIV)/interleukin-2 (IL-2)/IL-15, SIV Gag/Pol/Env recombinant modified vaccinia virus Ankara (rMVA), and AT-2 SIV(mac239) inactivated particles was compared in rhesus macaques after low-dose vagi...

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Detalhes bibliográficos
Main Authors: Manrique, Mariana, Kozlowski, Pamela A., Cobo-Molinos, Antonio, Wang, Shainn-Wei, Wilson, Robert L., Martinez-Viedma, Maria del Pilar, Montefiori, David C., Carville, Angela, Aldovini, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911749/
https://ncbi.nlm.nih.gov/pubmed/24155376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02523-13
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