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Generation of a Complete Single-Gene Knockout Bacterial Artificial Chromosome Library of Cowpox Virus and Identification of Its Essential Genes

Cowpox virus (CPXV) belongs to the genus Orthopoxvirus in the Poxviridae family. It infects a broad range of vertebrates and can cause zoonotic infections. CPXV has the largest genome among the orthopoxviruses and is therefore considered to have the most complete set of genes of all members of the g...

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Detalhes bibliográficos
Main Authors: Xu, Zhiyong, Zikos, Dimitrios, Osterrieder, Nikolaus, Tischer, B. Karsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911729/
https://ncbi.nlm.nih.gov/pubmed/24155400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02385-13
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