Human T-Cell Leukemia/Lymphoma Virus Type 1 p30, but Not p12/p8, Counteracts Toll-Like Receptor 3 (TLR3) and TLR4 Signaling in Human Monocytes and Dendritic Cells

The human T-cell leukemia/lymphoma virus type 1 (HTLV-1) p30 protein, essential for virus infectivity in vivo, is required for efficient infection of human dendritic cells (DCs) but not B and T cells in vitro. We used a human monocytic cell line, THP-1, and dendritic cells to study the mechanism of...

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Detalhes bibliográficos
Main Authors: Fenizia, Claudio, Fiocchi, Martina, Jones, Kathryn, Parks, Robyn Washington, Ceribelli, Michele, Chevalier, Sebastien A., Edwards, Dustin, Ruscetti, Francis, Pise-Masison, Cynthia A., Franchini, Genoveffa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911690/
https://ncbi.nlm.nih.gov/pubmed/24155397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01788-13
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