Role of Palatine Tonsils as a Prion Entry Site in Classical and Atypical Experimental Sheep Scrapie

Atypical and classical scrapie-infected sheep brain tissue was monolaterally injected into the tonsils of lambs to investigate their role as a prion entry point. We first detected classical PrP(Sc) within the inoculated tonsil and in the ipsilateral retropharyngeal lymph node at 3 months postinocula...

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Detalhes bibliográficos
Main Authors: Cancedda, Maria G., Di Guardo, Giovanni, Chiocchetti, Roberto, Demontis, Francesca, Marruchella, Giuseppe, Sorteni, Caterina, Maestrale, Caterina, Lai, Alfio, Ligios, Ciriaco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Prions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911675/
https://ncbi.nlm.nih.gov/pubmed/24198416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02750-13
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