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Intraepithelial and Interstitial Deposition of Pathological Prion Protein in Kidneys of Scrapie-Affected Sheep

Prions have been documented in extra-neuronal and extra-lymphatic tissues of humans and various ruminants affected by Transmissible Spongiform Encephalopathy (TSE). The presence of prion infectivity detected in cervid and ovine blood tempted us to reason that kidney, the organ filtrating blood deriv...

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Main Authors: Ligios, Ciriaco, Cancedda, Giovanna Maria, Margalith, Ilan, Santucciu, Cinzia, Madau, Laura, Maestrale, Caterina, Basagni, Massimo, Saba, Mariangela, Heikenwalder, Mathias
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2007
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964536/
https://ncbi.nlm.nih.gov/pubmed/17848990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000859
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