Differential Impact of Magnitude, Polyfunctional Capacity, and Specificity of HIV-Specific CD8(+) T Cell Responses on HIV Set Point

Defining the characteristics of HIV-specific CD8(+) T cell responses that lead to viral control is crucial for vaccine development. We evaluated the differential impact of magnitude, polyfunctional capacity, and specificity of the CD8(+) response at approximately 6 months postinfection on the viral...

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Main Authors: Riou, Catherine, Burgers, Wendy A., Mlisana, Koleka, Koup, Richard A., Roederer, Mario, Abdool Karim, Salim S., Williamson, Carolyn, Gray, Clive M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Cellular Response to Infection
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911608/
https://ncbi.nlm.nih.gov/pubmed/24227857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02968-13
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