Comparative Analysis of Hepatitis B Virus Polymerase Sequences Required for Viral RNA Binding, RNA Packaging, and Protein Priming

Hepatitis B virus replicates a DNA genome through reverse transcription of a pregenomic RNA (pgRNA) by using a multifunctional polymerase (HP). A critical function of HP is its specific association with a viral RNA signal, termed ε (Hε), located on pgRNA, which is required for specific packaging of...

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Päätekijät: Jones, Scott A., Clark, Daniel N., Cao, Feng, Tavis, John E., Hu, Jianming
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Genome Replication and Regulation of Viral Gene Expression
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911602/
https://ncbi.nlm.nih.gov/pubmed/24227865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02852-13
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