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Processing of the L1 52/55k Protein by the Adenovirus Protease: a New Substrate and New Insights into Virion Maturation

Late in adenovirus assembly, the viral protease (AVP) becomes activated and cleaves multiple copies of three capsid and three core proteins. Proteolytic maturation is an absolute requirement to render the viral particle infectious. We show here that the L1 52/55k protein, which is present in empty c...

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Detalhes bibliográficos
Main Authors: Pérez-Berná, Ana J., Mangel, Walter F., McGrath, William J., Graziano, Vito, Flint, Jane, San Martín, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911601/
https://ncbi.nlm.nih.gov/pubmed/24227847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02884-13
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