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First generation inhibitors of the adenovirus proteinase

As there are more than 50 Adenovirus serotypes, the likelihood of developing an effective vaccine is low. Here we describe inhibitors of the adenovirus proteinase (AVP) with the ultimate objective of developing anti-adenovirus agents. Inhibitors were identified via structure-based drug design using...

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Bibliografiske detaljer
Main Authors: McGrath, William J., Graziano, Vito, Zabrocka, Katarzyna, Mangel, Walter F.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810942/
https://ncbi.nlm.nih.gov/pubmed/23711373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.05.033
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