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First generation inhibitors of the adenovirus proteinase

As there are more than 50 Adenovirus serotypes, the likelihood of developing an effective vaccine is low. Here we describe inhibitors of the adenovirus proteinase (AVP) with the ultimate objective of developing anti-adenovirus agents. Inhibitors were identified via structure-based drug design using...

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Detalhes bibliográficos
Main Authors: McGrath, William J., Graziano, Vito, Zabrocka, Katarzyna, Mangel, Walter F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810942/
https://ncbi.nlm.nih.gov/pubmed/23711373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.05.033
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