A Vaccine against CCR5 Protects a Subset of Macaques upon Intravaginal Challenge with Simian Immunodeficiency Virus SIVmac251

As an alternative to targeting human immunodeficiency virus (HIV), we have developed vaccines targeting CCR5, a self-protein critically involved in HIV replication and pathogenesis. By displaying peptides derived from CCR5 at high density on the surface of virus-like particles, we can efficiently in...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Van Rompay, Koen K. A., Hunter, Zoe, Jayashankar, Kartika, Peabody, Julianne, Montefiori, David, LaBranche, Celia C., Keele, Brandon F., Jensen, Kara, Abel, Kristina, Chackerian, Bryce
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2014
Θέματα:
Vaccines and Antiviral Agents
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911553/
https://ncbi.nlm.nih.gov/pubmed/24307581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02447-13
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