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STAT1 Interaction with E3-14.7K in Monocytes Affects the Efficacy of Oncolytic Adenovirus

Oncolytic viruses based on adenovirus type 5 (Ad5) have been developed as a new class of therapeutic agents for cancers that are resistant to conventional therapies. Clinical experience shows that these agents are safe, but virotherapy alone has not achieved long-term cure in cancer patients. The va...

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Autors principals: Spurrell, Emma, Gangeswaran, Rathi, Wang, Pengju, Cao, Fengyu, Gao, Dongling, Feng, Baisui, Wold, William, Tollefson, Ann, Lemoine, Nicholas R., Wang, Yaohe
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911530/
https://ncbi.nlm.nih.gov/pubmed/24335311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02829-13
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