CEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells

The changes in cancer cell surface molecules and intracellular signaling pathways during tumorigenesis make delivery of adenovirus-based cancer therapies inefficient. Here we have identified carcinoembryonic antigen–related cell adhesion molecule 6 (CEACAM6) as a cellular protein that restricts the...

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Hauptverfasser: Wang, Yaohe, Gangeswaran, Rathi, Zhao, Xingbo, Wang, Pengju, Tysome, James, Bhakta, Vipul, Yuan, Ming, Chikkanna-Gowda, C.P., Jiang, Guozhong, Gao, Dongling, Cao, Fengyu, Francis, Jennelle, Yu, Jinxia, Liu, Kangdong, Yang, Hongyan, Zhang, Yunhan, Zang, Weidong, Chelala, Claude, Dong, Ziming, Lemoine, Nick
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689137/
https://ncbi.nlm.nih.gov/pubmed/19411761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37905
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