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Rad53 Downregulates Mitotic Gene Transcription by Inhibiting the Transcriptional Activator Ndd1
The 33 genes in the Saccharomyces cerevisiae mitotic CLB2 transcription cluster have been known to be downregulated by the DNA damage checkpoint for many years. Here, we show that this is mediated by the checkpoint kinase Rad53 and the dedicated transcriptional activator of the cluster, Ndd1. Ndd1 i...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3911491/ https://ncbi.nlm.nih.gov/pubmed/24324011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01056-13 |
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