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ELL Inhibits E2F1 Transcriptional Activity by Enhancing E2F1 Deacetylation via Recruitment of Histone Deacetylase 1

ELL (eleven-nineteen lysine-rich leukemia protein) was first identified as a translocation partner of MLL in acute myeloid leukemia; however, the exact mechanism of its action has remained elusive. In this study, we identified ELL as a direct downstream target gene of E2F1. Coimmunoprecipitation ass...

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主要な著者: Zhang, Wei, Ji, Wei, Liu, Xing, Ouyang, Gang, Xiao, Wuhan
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911481/
https://ncbi.nlm.nih.gov/pubmed/24344198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00878-13
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