Utility of Detection of Telaprevir-Resistant Variants for Prediction of Efficacy of Treatment of Hepatitis C Virus Genotype 1 Infection

The clinical usefulness of detecting telaprevir-resistant variants is unclear. Two hundred fifty-two Japanese patients infected with hepatitis C virus (HCV) genotype 1b received triple therapy with telaprevir–peginterferon (PEG-IFN)–ribavirin and were evaluated for telaprevir-resistant variants by d...

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Main Authors: Akuta, Norio, Suzuki, Fumitaka, Fukushima, Taito, Kawamura, Yusuke, Sezaki, Hitomi, Suzuki, Yoshiyuki, Hosaka, Tetsuya, Kobayashi, Masahiro, Hara, Tasuku, Kobayashi, Mariko, Saitoh, Satoshi, Arase, Yasuji, Ikeda, Kenji, Kumada, Hiromitsu
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Virology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911448/
https://ncbi.nlm.nih.gov/pubmed/24197875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02371-13
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