Impact of Mutations at Amino Acid 70 in Hepatitis C Virus (HCV) Genotype 1b Core Region on Hepatocarcinogenesis following Eradication of HCV RNA

The impact of the HCV genotype 1b core amino acid (aa) 70 mutant on the cumulative rate of hepatocellular carcinoma following eradication of HCV RNA by antiviral therapy was investigated with the Q-Invader assay. Multivariate analysis based on 649 patients indicated that a core aa70 Q-Invader mutant...

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Veröffentlicht in:J Clin Microbiol
Hauptverfasser: Akuta, Norio, Suzuki, Fumitaka, Kobayashi, Masahiro, Sezaki, Hitomi, Kawamura, Yusuke, Hosaka, Tetsuya, Kobayashi, Mariko, Saitoh, Satoshi, Suzuki, Yoshiyuki, Arase, Yasuji, Ikeda, Kenji, Kumada, Hiromitsu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Virology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540910/
https://ncbi.nlm.nih.gov/pubmed/26135874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01457-15
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