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Nonrandom association of a type II procollagen genotype with achondroplasia.

Achondroplasia is an autosomal dominant disorder that involves defective endochondral bone formation. Type II collagen is the predominant collagen of cartilage. We found a HindIII polymorphic site in the normal Caucasian population by using the type II procollagen gene probe pgHCol(II)A. The presenc...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Eng, C E, Pauli, R M, Strom, C M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2991928/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.16.5465
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